You give chemotherapy. It damages cancer cell DNA. The…

You give chemotherapy. It damages cancer cell DNA. The cancer repairs the damage. And survives. This is one of the most fundamental mechanisms of treatment resistance and one of the most frustrating problems in oncology. Researchers found that a compound called UNI418 can disrupt this DNA repair ability in cancer cells, leaving them more exposed to the damage that therapy is meant to cause. By blocking the repair mechanism, not the cancer itse