What Ozempic Users Are Really Experiencing. AI Scanned…

What Ozempic Users Are Really Experiencing. AI Scanned 400,000 Reddit Posts to Find Out. Endocrinology / Pharmacovigilance | May 24, 2026 | Source: University of Pennsylvania / Nature Health Semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) are among the most prescribed drugs in the world right now. Clinical trials identified the major side effects including nausea, vomiting, diarrhoea and those are on the label. But what are patients actually experiencing? And what aren't they telling their doctors? Researchers at the University of Pennsylvania used AI to analyse over 400,000 Reddit posts from nearly 70,000 users across five years. Their findings, published in Nature Health, reveal a pattern of symptoms that clinical trials may be missing. About 44% of users in the study mentioned at least one side effect. The most common: gastrointestinal symptoms, confirming the AI was detecting real signals. But beyond the expected, several less-documented complaints appeared consistently: Menstrual irregularit