Ibuprofen vs Paracetamol for Children’s Pain: What Does…

Ibuprofen vs Paracetamol for Children’s Pain: What Does New Evidence Say? Ibuprofen and acetaminophen, commonly known as paracetamol, are among the most widely used medicines for managing mild to moderate pain in children. A new systematic review and meta-analysis compared their short-term safety in paediatric and acute pain settings. The study, published in the British Journal of Clinical Pharmacology, reviewed randomized controlled trials involving children and adolescents aged 0–18 years. Researchers also included some acute pain studies from broader age groups when paediatric-relevant safety data could be extracted. The review included 15 studies with a total of 2,847 participants. These studies covered different pain settings, including postoperative pain, musculoskeletal injury, orthodontic pain, and emergency department care.