Faster Prostate Cancer Radiotherapy Improves Bowel Quality…

Faster Prostate Cancer Radiotherapy Improves Bowel Quality of Life, But Doesn't Beat Standard Treatment on Cancer Control Stereotactic body radiotherapy, delivered in just 5 sessions, has been gaining interest as a faster alternative to standard prostate cancer radiation, which typically requires 20 to 28 sessions. A major international randomized trial published in JAMA now offers the clearest comparison yet between the two approaches, and the results are genuinely mixed. The trial, NRG-GU005: This was a large phase 3, international, open label randomized clinical trial, conducted across 136 centers in Asia, Canada, Europe, and the United States. The study enrolled patients with localized, favorable intermediate risk prostate cancer, activated in November 2017 and closed to enrollment in June 2022. What was compared: A total of 698 patients were randomized to receive either stereotactic body radiotherapy, a shorter, more intensive 5 session course, or moderately hypofractionated intensity modulated radiation therapy, a more standard 20 to 28 session course. What researchers measur