AI Has Decoded a Key Genetic "On Switch" Found in 60% of…

AI Has Decoded a Key Genetic "On Switch" Found in 60% of Human Genes Healthy growth and development depend on tens of thousands of genes switching on at exactly the right time and place. A new study from UC San Diego, using AI to analyze roughly 500,000 DNA sequences, has decoded the genetic signature of one of the most important of these switches, called the initiator, found in an estimated 60% of human genes. Why this matters at a basic biology level: Specific regions of DNA coordinate when genes activate, guiding the production of enzymes, hormones, proteins, and other molecules cells depend on. When this activation process goes wrong, cells can malfunction, contributing to diseases including cancer. What researchers actually did: The team used high throughput DNA sequencing to measure gene expression activity across approximately 500,000 different versions of a DNA element called th